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Borage seed oil is made from the seeds of the borage plants. Borage seed oil contains very high levels of two types of polyunsaturated omega-6 essential fatty acids, 20–26% gamma-linolenic acid (GLA) and linolenic acid (LA, which your body converts to GLA). GLA is an essential fatty acid that’s important for maintaining a joint’s cell structure and function. Your body converts it into hormone-like substances called prostaglandins, which regulate your immune system and fight joint inflammation. GLA might also suppress inflammatory responses by directly acting on some inflammatory cells